Schon, Arne: search on Z-Library

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1

Some Binding-Related Drug Properties are Dependent on Thermodynamic Signature

Arne Schön, Navid Madani, Amos B. Smith, Judith M. Lalonde, Ernesto Freire

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 248 KB

english, 2011

2

Strategies for targeting HIV-1 envelope glycoprotein gp120 in the development of new antivirals

Schön, Arne, Freire, Ernesto

Journal:

Future HIV Therapy

Year:

2007

Language:

english

File:

PDF, 1.18 MB

english, 2007

3

Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction

Pfeiffer, Susanne, Krüger, Jacqueline, Maierhofer, Anna, Böttcher, Yvonne, Klöting, Nora, El Hajj, Nady, Schleinitz, Dorit, Schön, Michael R., Dietrich, Arne, Fasshauer, Mathias, Lohmann, Tobias, Dreß

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 608 KB

english, 2016

4

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

Lai, Yen-Ting, Wang, Tao, O’Dell, Sijy, Louder, Mark K., Schön, Arne, Cheung, Crystal S. F., Chuang, Gwo-Yu, Druz, Aliaksandr, Lin, Bob, McKee, Krisha, Peng, Dongjun, Yang, Yongping, Zhang, Baoshan, H

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 4.76 MB

english, 2019

5

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex vivo and Distribution in vivo

Xu, Qingguo, Ensign, Laura M., Boylan, Nicholas J., Schön, Arne, Gong, Xiaoqun, Yang, Jeh-Chang, Lamb, Nicholas W., Cai, Shutian, Yu, Tao, Freire, Ernesto, Hanes, Justin

Journal:

Year:

2015

Language:

english

File:

PDF, 2.02 MB

english, 2015

6

Publisher Correction: The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

Herschhorn, Alon, Gu, Christopher, Moraca, Francesca, Ma, Xiaochu, Farrell, Mark, Smith, Amos B., Pancera, Marie, Kwong, Peter D., Schön, Arne, Freire, Ernesto, Abrams, Cameron, Blanchard, Scott C., M

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 265 KB

english, 2018

7

Long term stability of a HIV-1 neutralizing monoclonal antibody using isothermal calorimetry

Clarkson, Benjamin R., Chaudhuri, Rajoshi, Schön, Arne, Kueltzo, Lisa, Freire, Ernesto

Journal:

Analytical Biochemistry

Year:

2018

Language:

english

File:

PDF, 1.51 MB

english, 2018

8

Telomere length differences between subcutaneous and visceral adipose tissue in humans

Lakowa, Nicole, Trieu, Nhu, Flehmig, Gesine, Lohmann, Tobias, Schön, Michael R., Dietrich, Arne, Zeplin, Philip Helge, Langer, Stefan, Stumvoll, Michael, Blüher, Matthias, Klöting, Nora

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 710 KB

english, 2015

9

The effect of temperature on metabolism in 3T3 cells and SV40-transformed 3T3 cells as measured by microcalorimetry

Per Lönnbro, Arne Schön

Journal:

Thermochimica Acta

Year:

1990

Language:

english

File:

PDF, 324 KB

english, 1990

10

Small-Molecule CD4 Mimics Interact with a Highly Conserved Pocket on HIV-1 gp120

Navid Madani, Arne Schön, Amy M. Princiotto, Judith M. LaLonde, Joel R. Courter, Takahiro Soeta, Danny Ng, Liping Wang, Evan T. Brower, Shi-Hua Xiang, Young Do Kwon, Chih-chin Huang, Richard Wyatt, Pe

Journal:

Year:

2008

Language:

english

File:

PDF, 1.10 MB

english, 2008

11

Conformational stability and self-association equilibrium in biologics

Clarkson, Benjamin R., Schön, Arne, Freire, Ernesto

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

12

Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening

Judith M. LaLonde, Mark A. Elban, Joel R. Courter, Akihiro Sugawara, Takahiro Soeta, Navid Madani, Amy M. Princiotto, Young Do Kwon, Peter D. Kwong, Arne Schön, Ernesto Freire, Joseph Sodroski, Amos B

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 880 KB

english, 2011

13

Non-natural Peptide Triazole Antagonists of HIV-1 Envelope gp120

Kamanna, Kantharaju, Aneja, Rachna, Duffy, Caitlin, Kubinski, Pamela, Rodrigo Moreira, Diogo, Bailey, Lauren D., McFadden, Karyn, Schön, Arne, Holmes, Andrew, Tuzer, Ferit, Contarino, Mark, Freire, Er

Journal:

Year:

2013

Language:

english

File:

PDF, 661 KB

english, 2013

14

Antibody-induced apoptosis in a human leukemia cell line is energy dependent: thermochemical analysis of cellular metabolism

Wallén-Öhman, Marie, Lönnbro, Per, Schön, Arne, Borrebaeck, Carl A.K.

Journal:

Year:

1993

Language:

english

File:

PDF, 582 KB

english, 1993

15

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env

Georgiev, Ivelin S., Joyce, M. Gordon, Yang, Yongping, Sastry, Mallika, Zhang, Baoshan, Baxa, Ulrich, Chen, Rita E., Druz, Aliaksandr, Lees, Christopher R., Narpala, Sandeep, Schön, Arne, Van Galen, J

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 2.46 MB

english, 2015

16

Establishment and characterization of osteogenic cell lines from a spontaneous murine osteosarcoma

Jörg Schmidt, Günter P. Strauß, Annemarie Schön, Arne Luz, A. Beatrice Murray, Antonella Melchiori, Ottavia Aresu, Volker Erfle

Journal:

Differentiation

Year:

1988

Language:

english

File:

PDF, 3.84 MB

english, 1988

17

Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits

Brune, Jakob E., Kern, Matthias, Kunath, Anne, Flehmig, Gesine, Schön, Michael R., Lohmann, Tobias, Dressler, Miriam, Dietrich, Arne, Fasshauer, Mathias, Kovacs, Peter, Stumvoll, Michael, Blüher, Matt

Journal:

Year:

2016

Language:

english

File:

PDF, 295 KB

english, 2016

18

Evidence that Membrane Insertion of the Cytosolic Domain of Bcl-xL is Governed by an Electrostatic Mechanism

Guruvasuthevan R. Thuduppathy, Jeffrey W. Craig, Victoria Kholodenko, Arne Schon, R. Blake Hill

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 454 KB

english, 2006

19

An unexpected temperature effect obtained on enantiomer separation using CBH i-silica as a chiral stationary phase: Increase in retention and enantioselectivity at elevated column temperature: A chromatographic and microcalorimetric study

Stefan Jönsson, Arne Schön, Roland Isaksson, Curt Pettersson, Göran Pettersson

Journal:

Year:

1992

Language:

english

File:

PDF, 323 KB

english, 1992

20

Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets

Hiroyasu Ohtaka, Salman Muzammil, Arne Schön, Adrian Velazquez-Campoy, Sonia Vega, Ernesto Freire

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2004

Language:

english

File:

PDF, 237 KB

english, 2004

21

Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: Design, synthesis, biological evaluation, and docking studies

Thanigaimalai, Pillaiyar, Konno, Sho, Yamamoto, Takehito, Koiwai, Yuji, Taguchi, Akihiro, Takayama, Kentaro, Yakushiji, Fumika, Akaji, Kenichi, Chen, Shen-En, Naser-Tavakolian, Aurash, Schön, Arne, Fr

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.27 MB

english, 2013

22

CD4 mimetics sensitize HIV-1-infected cells to ADCC

Richard, Jonathan, Veillette, Maxime, Brassard, Nathalie, Iyer, Shilpa S., Roger, Michel, Martin, Loïc, Pazgier, Marzena, Schön, Arne, Freire, Ernesto, Routy, Jean-Pierre, Smith, Amos B., Park, Jongwo

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

23

The capacity of reducing-equivalent shuttles limits glycolysis during ethanol oxidation

Michael N. Berry, Roland B. Gregory, Anthony R. Grivell, John W. Phillips, Arne SchÖN

Journal:

Year:

1994

Language:

english

File:

PDF, 873 KB

english, 1994

24

Ligand binding analysis and screening by chemical denaturation shift

Schön, Arne, Brown, Richard K., Hutchins, Burleigh M., Freire, Ernesto

Journal:

Analytical Biochemistry

Year:

2013

Language:

english

File:

PDF, 1011 KB

english, 2013

25

Chemical denaturation as a tool in the formulation optimization of biologics

Freire, Ernesto, Schön, Arne, Hutchins, Burleigh M., Brown, Richard K.

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 621 KB

english, 2013

26

Discrimination of Potent Inhibitors of Toxoplasma gondii Enoyl-Acyl Carrier Protein Reductase by a Thermal Shift Assay

Afanador, Gustavo A., Muench, Stephen P., McPhillie, Martin, Fomovska, Alina, Schön, Arne, Zhou, Ying, Cheng, Gang, Stec, Jozef, Freundlich, Joel S., Shieh, Hong-Ming, Anderson, John W., Jacobus, Davi

Journal:

Year:

2013

Language:

english

File:

PDF, 2.67 MB

english, 2013

27

IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits

Rohde, Kerstin, Klös, Matthias, Hopp, Lydia, Liu, Xuanshi, Keller, Maria, Stumvoll, Michael, Dietrich, Arne, Schön, Michael R., Gärtner, Daniel, Lohmann, Tobias, Dreßler, Miriam, Kovacs, Peter, Binder

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

28

Effects of pH-variations on the kinetics of growth and energy metabolism in cultured T-lymphoma cells: A microcalorimetric study

Per Bäckman, Takayoshi Kimura, Arne Schön, Ingemar Wadsö

Journal:

Journal of Cellular Physiology

Year:

1992

Language:

english

File:

PDF, 508 KB

english, 1992

29

The binding of HIV-1 protease inhibitors to human serum proteins

Arne Schön, Maria del Mar Ingaramo, Ernesto Freire

Journal:

Biophysical Chemistry

Year:

2003

Language:

english

File:

PDF, 152 KB

english, 2003

30

Optimization of Small Molecules That Sensitize HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity

Grenier, Melissa C., Ding, Shilei, Vézina, Dani, Chapleau, Jean-Philippe, Tolbert, William D., Sherburn, Rebekah, Schön, Arne, Somisetti, Sambasivarao, Abrams, Cameron F., Pazgier, Marzena, Finzi, And

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 4.32 MB

english, 2019

31

Adipose tissue depot specific promoter methylation ofTMEM18

Rohde, Kerstin, Keller, Maria, Klös, Matthias, Schleinitz, Dorit, Dietrich, Arne, Schön, Michael R., Gärtner, Daniel, Lohmann, Tobias, Dreßler, Miriam, Stumvoll, Michael, Kovacs, Peter, Blüher, Matthi

Journal:

Journal of Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 380 KB

english, 2014

32

Emergence of a vancomycin-variable Enterococcus faecium ST1421 strain containing a deletion in vanX

Hansen, Thomas Arn, Pedersen, Martin Schou, Nielsen, Lone Gilmor, Ma, Chih Man German, Søes, Lillian Marie, Worning, Peder, Østergaard, Christian, Westh, Henrik, Pinholt, Mette, Schønning, Kristian

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2018

Language:

english

File:

PDF, 499 KB

english, 2018

33

Three easy pieces

Schön, Arne, Freire, Ernesto

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2016

Language:

english

File:

PDF, 1.00 MB

english, 2016

34

Fas and FasL Expression in Human Adipose Tissue Is Related to Obesity, Insulin Resistance, and Type 2 Diabetes

Blüher, Matthias, Klöting, Nora, Wueest, Stephan, Schoenle, Eugen J., Schön, Michael R., Dietrich, Arne, Fasshauer, Mathias, Stumvoll, Michael, Konrad, Daniel

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 226 KB

english, 2014

35

Effects of Weight Loss and Exercise on Apelin Serum Concentrations and Adipose Tissue Expression in Human Obesity

Krist, Joanna, Wieder, Katharina, Klöting, Nora, Oberbach, Andreas, Kralisch, Susan, Wiesner, Tobias, Schön, Michael R., Gärtner, Daniel, Dietrich, Arne, Shang, Edward, Lohmann, Tobias, Dreßler, Miria

Journal:

Year:

2013

Language:

english

File:

PDF, 639 KB

english, 2013

36

Bioinspired supramolecular engineering of self-assembling immunofibers for high affinity binding of immunoglobulin G

Li, Yi, Lock, Lye Lin, Wang, Yuzhu, Ou, Shih-Hao, Stern, David, Schön, Arne, Freire, Ernesto, Xu, Xuankuo, Ghose, Sanchayita, Li, Zheng Jian, Cui, Honggang

Journal:

Year:

2018

Language:

english

File:

PDF, 4.66 MB

english, 2018

37

SOSIP changes affect human immunodeficiency virus (HIV-1) envelope glycoprotein conformation and CD4 engagement

Alsahafi, Nirmin, Anand, Sai Priya, Castillo-Menendez, Luis, Verly, Myriam Maude, Medjahed, Halima, Prévost, Jérémie, Herschhorn, Alon, Richard, Jonathan, Schön, Arne, Melillo, Bruno, Freire, Ernesto,

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 970 KB

english, 2018

38

The Active Core in a Triazole Peptide Dual-Site Antagonist of HIV-1 gp120

Dr. Muddegowda Umashankara, Karyn McFadden, Isaac Zentner, Dr. Arne Schön, Dr. Srivats Rajagopal, Ferit Tuzer, Syna A. Kuriakose, Dr. Mark Contarino, Dr. Judith LaLonde, Prof. Ernesto Freire, Prof. Ir

Journal:

Year:

2010

Language:

english

File:

PDF, 835 KB

english, 2010

39

Optimization of CD4/gp120 Inhibitors by Thermodynamic-Guided Alanine-Scanning Mutagenesis

Liu, Yingyun, Schön, Arne, Freire, Ernesto

Journal:

Chemical Biology & Drug Design

Year:

2013

Language:

english

File:

PDF, 704 KB

english, 2013

40

Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition

Melillo, Bruno, Liang, Shuaiyi, Park, Jongwoo, Schön, Arne, Courter, Joel R., LaLonde, Judith M., Wendler, Daniel J., Princiotto, Amy M., Seaman, Michael S., Freire, Ernesto, Sodroski, Joseph, Madani,

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 2.17 MB

english, 2016

41

Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-ray and Thermodynamic Characterization

LaLonde, Judith M., Le-Khac, Matthew, Jones, David M., Courter, Joel R., Park, Jongwoo, Schön, Arne, Princiotto, Amy M., Wu, Xueling, Mascola, John R., Freire, Ernesto, Sodroski, Joseph, Madani, Navid

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 2.46 MB

english, 2013

42

Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

Kisalu, Neville K, Idris, Azza H, Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J, Sack, Brandon K, Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R, Miller, Alex B, Gregory, Jaso

Journal:

Nature Medicine

Year:

2018

Language:

english

File:

PDF, 674 KB

english, 2018

43

Pigmented Basal Cell Carcinomas 15 Years After Orbital Radiation Therapy for Graves Ophthalmopathy

Haenssle, Holger A., Richter, Arne, Buhl, Timo, Haas, Ellen, Holzkamp, Ricarda, Emmert, Steffen, Schön, Michael P.

Journal:

Archives of Dermatology

Year:

2011

Language:

english

File:

PDF, 456 KB

english, 2011

44

Enthalpy screen of drug candidates

Schön, Arne, Freire, Ernesto

Journal:

Analytical Biochemistry

Year:

2016

Language:

english

File:

PDF, 1.10 MB

english, 2016

45

Interactions of HIV-1 Proteins gp120 and Nef with Cellular Partners Define a Novel Allosteric Paradigm

A. Leavitt, Stephanie, Schon, Arne, C. Klein, Jeffrey, Manjappara, Uma, M. Chaiken, Irwin, Freire, Ernesto

Journal:

Current Protein & Peptide Science

Year:

2004

Language:

english

File:

PDF, 212 KB

english, 2004

46

Microcalorimetric evaluation of the effects of methotrexate and 6-thioguanine on sensitive T-lymphoma cells and on a methotrexate-resistant subline

Jordi Bermudez, Per Bäckman, Arne Schön

Journal:

Cell Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 616 KB

english, 1992

47

Photochemical Control of RNA Structure by Disrupting π-Stacking

Resendiz, Marino J. E., Schön, Arne, Freire, Ernesto, Greenberg, Marc M.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 921 KB

english, 2012

48

Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist

Courter, Joel R., Madani, Navid, Sodroski, Joseph, Schön, Arne, Freire, Ernesto, Kwong, Peter D., Hendrickson, Wayne A., Chaiken, Irwin M., LaLonde, Judith M., Smith, Amos B.

Journal:

Accounts of Chemical Research

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

49

HIV-1 Vif N-terminal Motif is required for recruitment of Cul5 to Suppress APOBEC3

Evans, Sean L, Schön, Arne, Gao, Qimeng, Han, Xue, Zhou, Xiaohong, Freire, Ernesto, Yu, Xiao-Fang

Journal:

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

50

Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120

Hyun-Su Lee, Mark Contarino, M. Umashankara, Arne Schön, Ernesto Freire, Amos B. Smith, Irwin M. Chaiken, Lynn S. Penn

Journal:

Analytical and Bioanalytical Chemistry

Year:

2010

Language:

english

File:

PDF, 346 KB

english, 2010

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